New antibiotic combinations

The eternal quest for new antibiotic combinations!

Antibiotic resistance is a growing concern worldwide, and the development of new antibiotic combinations is crucial to combat this issue. Here are some recent examples of new antibiotic combinations:

  1. Daptomycin + ceftaroline: A combination of daptomycin, a lipopeptide antibiotic, and ceftaroline, a cephalosporin antibiotic, has shown promising results against methicillin-resistant Staphylococcus aureus (MRSA) and other Gram-positive bacteria.
  2. Ceftobiprole + tigecycline: This combination has been tested against MRSA and other Gram-positive bacteria, including those resistant to vancomycin. Ceftobiprole is a cephalosporin antibiotic, while tigecycline is a glycylcycline antibiotic.
  3. Meropenem + vaborbactam: This combination has been shown to be effective against carbapenem-resistant Enterobacteriaceae (CRE) and other Gram-negative bacteria. Meropenem is a carbapenem antibiotic, while vaborbactam is a beta-lactamase inhibitor.
  4. Ceftazidime + avibactam: This combination has been tested against CRE and other Gram-negative bacteria, including those resistant to ceftazidime. Ceftazidime is a cephalosporin antibiotic, while avibactam is a beta-lactamase inhibitor.
  5. Piperacillin + tazobactam + ciprofloxacin: This combination has been shown to be effective against Pseudomonas aeruginosa and other Gram-negative bacteria, including those resistant to piperacillin and tazobactam.
  6. Ceftaroline + sulbactam: This combination has been tested against MRSA and other Gram-positive bacteria, including those resistant to ceftaroline. Ceftaroline is a cephalosporin antibiotic, while sulbactam is a beta-lactamase inhibitor.
  7. Doripenem + cilastatin: This combination has been shown to be effective against Pseudomonas aeruginosa and other Gram-negative bacteria, including those resistant to doripenem.
  8. Ceftobiprole + sulbactam: This combination has been tested against MRSA and other Gram-positive bacteria, including those resistant to ceftobiprole. Ceftobiprole is a cephalosporin antibiotic, while sulbactam is a beta-lactamase inhibitor.
  9. Meropenem + sulbactam: This combination has been shown to be effective against CRE and other Gram-negative bacteria, including those resistant to meropenem.
  10. Ceftazidime + sulbactam + ciprofloxacin: This combination has been tested against CRE and other Gram-negative bacteria, including those resistant to ceftazidime and ciprofloxacin.

These are just a few examples of new antibiotic combinations being developed to combat antibiotic resistance. It's essential to continue researching and developing new combinations to stay ahead of the evolving threat of antibiotic resistance.