Effect of giving new born opv twice within 5days

Giving a newborn OPV (Oral Poliovirus Vaccine) twice within 5 days is not a recommended or standard practice. In fact, the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) recommend a single dose of OPV at birth, followed by a second dose at 6-8 weeks of age.

Giving OPV twice within 5 days may have several potential effects on the newborn:

  1. Increased risk of adverse reactions: OPV is a live, attenuated vaccine, and giving it twice within a short period may increase the risk of adverse reactions, such as fever, fussiness, and vomiting.
  2. Reduced immune response: Giving OPV too frequently may reduce the immune response to the vaccine, making it less effective in providing protection against polio.
  3. Increased risk of vaccine-associated paralytic poliomyelitis (VAPP): VAPP is a rare but serious complication of OPV vaccination. Giving OPV twice within 5 days may increase the risk of VAPP, particularly in newborns who are more susceptible to the vaccine.
  4. Potential for vaccine interference: OPV is a live vaccine, and giving it too frequently may interfere with the immune response to other vaccines, such as the BCG vaccine, which is often given at birth.

The American Academy of Pediatrics (AAP) and the WHO recommend the following schedule for OPV vaccination:

It is essential to follow the recommended vaccination schedule to ensure the best possible protection against polio and to minimize the risk of adverse reactions. If you have concerns about your newborn's vaccination schedule, it is best to consult with your healthcare provider.