Cefixime oral suspension for new born
Cefixime is an antibiotic that is commonly used to treat bacterial infections in children, including newborns. However, its use in newborns requires careful consideration and close monitoring due to the potential risks and side effects.
Here are some key points to consider when using cefixime oral suspension in newborns:
Indications: Cefixime is indicated for the treatment of mild to moderate infections caused by susceptible bacteria, such as:
- Otitis media (middle ear infection)
- Pharyngitis (throat infection)
- Tonsillitis (tonsil infection)
- Sinusitis (sinus infection)
- Urinary tract infections (UTIs)
Dosing: The recommended dose of cefixime oral suspension for newborns is typically 20-40 mg/kg/day, divided into two doses every 12 hours. The dose may vary depending on the infant's weight and the severity of the infection.
Contraindications: Cefixime is contraindicated in newborns with a history of hypersensitivity to cephalosporins or penicillins.
Precautions: When using cefixime in newborns, the following precautions should be taken:
- Monitor for signs of allergic reactions, such as rash, hives, or difficulty breathing.
- Monitor for signs of gastrointestinal upset, such as diarrhea, vomiting, or abdominal pain.
- Monitor for signs of kidney or liver dysfunction, such as increased bilirubin levels or abnormal liver function tests.
- Avoid using cefixime in newborns with a history of gastrointestinal disease, such as necrotizing enterocolitis (NEC).
Side effects: Common side effects of cefixime in newborns include:
- Diarrhea
- Vomiting
- Abdominal pain
- Rash
- Hives
- Allergic reactions
Interactions: Cefixime may interact with other medications, such as:
- Probenecid: May increase the risk of kidney damage.
- Warfarin: May increase the risk of bleeding.
- Methotrexate: May increase the risk of toxicity.
Monitoring: When using cefixime in newborns, it is essential to monitor the infant's response to the medication, including:
- Clinical response to the infection
- Laboratory tests, such as complete blood counts, liver function tests, and kidney function tests
- Electrolyte levels, such as potassium and sodium
Conclusion: Cefixime oral suspension can be used to treat bacterial infections in newborns, but it requires careful consideration and close monitoring due to the potential risks and side effects. It is essential to weigh the benefits and risks of using cefixime in newborns and to monitor the infant's response to the medication closely.