A seminar on where will the new antimicrobials come from

Here's a potential seminar outline on "Where will the new antimicrobials come from?"

Title: "The Quest for New Antimicrobials: Exploring Emerging Sources and Strategies"

Objective: To discuss the current antimicrobial resistance crisis and explore innovative sources and strategies for discovering new antimicrobials.

Agenda:

I. Introduction (5 minutes)

• Overview of the antimicrobial resistance crisis and its consequences
• Importance of developing new antimicrobials to combat resistant bacteria

II. Current Sources of Antimicrobials (20 minutes)

• Overview of traditional sources of antimicrobials:
  • Natural products (e.g., antibiotics from soil, plants, and marine organisms)
  • Semi-synthetic derivatives of natural products
  • Synthetic antimicrobials
• Discussion of the limitations and challenges of these sources

III. Emerging Sources of Antimicrobials (30 minutes)

• Exploration of new sources of antimicrobials:
  • Synthetic biology and gene editing (e.g., CRISPR)
  • Microbial communities and metagenomics
  • Fungi and fungal-derived compounds
  • Marine organisms and marine-derived compounds
  • Plant-based antimicrobials (e.g., essential oils, polyphenols)
• Discussion of the potential and challenges of these emerging sources

IV. Strategies for Discovering New Antimicrobials (20 minutes)

• Overview of strategies for discovering new antimicrobials:
  • High-throughput screening (HTS) and combinatorial chemistry
  • Computational modeling and in silico screening
  • Collaborative research and open innovation
  • Public-private partnerships and funding initiatives
• Discussion of the strengths and limitations of each strategy

V. Case Studies and Success Stories (20 minutes)

• Presentation of successful examples of new antimicrobial discovery and development:
  • Natural products (e.g., daptomycin, vancomycin)
  • Synthetic antimicrobials (e.g., linezolid, telithromycin)
  • Emerging sources (e.g., CRISPR-derived antimicrobials, fungal-derived compounds)
• Discussion of the challenges and opportunities faced by these projects

VI. Conclusion and Future Directions (10 minutes)

• Recap of the seminar's key takeaways
• Discussion of the future of antimicrobial discovery and development
• Call to action for the audience to contribute to the quest for new antimicrobials

Speakers:

• Dr. Jane Smith, Microbiologist, University of [University Name]
• Dr. John Doe, Synthetic Biologist, [Company Name]
• Dr. Maria Rodriguez, Fungal Biologist, [Institution Name]
• Dr. David Lee, Computational Biologist, [University Name]

Target Audience:

• Researchers and scientists in the fields of microbiology, synthetic biology, and pharmaceutical development
• Industry professionals and entrepreneurs interested in antimicrobial discovery and development
• Students and early-career researchers looking to learn about the latest trends and opportunities in antimicrobial research

Materials:

• Seminar program and abstracts
• PowerPoint presentations and handouts
• List of references and resources for further reading
• Networking opportunities and refreshments