A new sulphatec flavone

A new sulfated flavone!

Sulfated flavones are a class of compounds that have been found to possess a range of biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties.

Here's a hypothetical example of a new sulfated flavone:

Name: Sulflavonin A

Structure:

Sulflavonin A is a sulfated flavone with the following structure:

C₂₁H₁₆O₁₁S

Synthesis:

Sulflavonin A can be synthesized through a multi-step reaction involving the sulfation of a flavone precursor, such as quercetin, with sulfuric acid and subsequent purification steps.

Biological Activity:

Preliminary studies have shown that Sulflavonin A exhibits potent antioxidant activity, with an IC₅₀ value of 2.5 μM against the DPPH radical. It also displays moderate anti-inflammatory activity, with an IC₅₀ value of 10 μM against the production of nitric oxide in lipopolysaccharide-stimulated RAW 264.7 macrophages.

Pharmacokinetic Properties:

Sulflavonin A has been found to have good oral bioavailability, with a peak plasma concentration (Cmax) of 1.2 μM and a half-life (t1/2) of 4.5 hours in rats.

Conclusion:

Sulflavonin A is a new sulfated flavone with promising antioxidant and anti-inflammatory activities. Further studies are needed to fully elucidate its biological effects and potential therapeutic applications.